甲型H1N1流感病毒RNA檢測試劑盒(PCR方法)

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甲型H1N1流感病毒RNA檢測試劑盒(PCR方法)

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甲型H1N1流感病毒RNA檢測試劑盒(PCR方法)

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】    楊永漢

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【騰訊  】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

以前的圖像試圖產(chǎn)生這種咀嚼控制中心的相對模糊的圖片。研究人員知道下頜和舌頭的肌肉運(yùn)動由一種稱為運(yùn)動神經(jīng)元的特殊神經(jīng)元控制，而這些反過來的運(yùn)動是由稱為前運(yùn)動神經(jīng)元的另一組神經(jīng)元控制。但這些連接的確切性質(zhì)——即哪一個(gè)前運(yùn)動神經(jīng)元連接到哪一個(gè)運(yùn)動神經(jīng)元——還沒有確定。
高級研究作者、杜克大學(xué)腦科學(xué)研究所的成員、神經(jīng)生物學(xué)的副教授王帆博士，已經(jīng)研究老鼠的神經(jīng)回路的映射多年。在她的指導(dǎo)下，斯坦尼克使用狂犬病毒的一種特殊形式，追蹤咀嚼運(yùn)動的起源。
狂犬病毒的工作原理是自然地向后跳跨神經(jīng)元，直到它已經(jīng)感染了受害者的整個(gè)大腦。在這項(xiàng)研究中，斯坦尼克采用了基因禁用版本狂犬病毒，這只能從肌肉跳轉(zhuǎn)到運(yùn)動神經(jīng)元，然后回到前運(yùn)動神經(jīng)元。該病毒還載有綠色或紅色熒光標(biāo)記，這使研究人員能夠看到它跳躍之后的位置。
斯坦尼克將這些熒光標(biāo)記的病毒注入兩個(gè)肌肉中，舌頭外伸頦舌肌和下頜閉合咬肌。他發(fā)現(xiàn)，一組前運(yùn)動神經(jīng)元同時(shí)連接到運(yùn)動神經(jīng)元調(diào)節(jié)下頜打開和引發(fā)舌頭伸出。同樣地，他發(fā)現(xiàn)另一組連接到這兩個(gè)運(yùn)動神經(jīng)元調(diào)節(jié)下頜閉合和負(fù)責(zé)舌頭的回縮。結(jié)果表明，協(xié)調(diào)舌頭和下頜的運(yùn)動的一種簡單方法通常能讓舌頭遠(yuǎn)離傷害。

Previous images attempted to produce a relatively blurred picture of this chewing control center. Researchers know that muscle movements in the jaw and tongue are controlled by a special type of neuron called motor neurons that are controlled by another group of neurons called preomotor neurons. But the exact nature of these connections - which motoneurons are connected to which an anterior motor neuron - has not been established.
Dr. Wang Fan, a senior research author and a member of the Duke University Institute for Brain Science and an associate professor of neurobiology, has been studying the mapping of neural circuits in mice for many years. Under her direction, Steinik uses a special form of rabies virus to track the origin of chewing motility.
The rabies virus works by naturally jumping back across the neuron until it has infected the victim's entire brain. In this study, Steinick used a genetically disabled version of rabies virus that can only jump from muscle to motor neurons before returning to motor neurons. The virus also carries a green or red fluorescent marker, which allows researchers to see where it jumps.
Steinnik injected these fluorescently-labeled viruses into both muscles, with the tongue extending to the genioglossus and the mandibular closed masseter. He found that a group of pre-motor neurons connected to motor neurons simultaneously regulate the opening of the lower jaw and trigger the tongue to stick out. Similarly, he found that another group connected to both motor neurons mediates mandibular closure and is responsible for the retraction of the tongue. The results show that a simple way of coordinating the movement of the tongue and jaw can usually keep the tongue away from injury.